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QuickView for matrix metalloproteinase 14;jsessionid=A00613594403ADC6B00D875F04440A42;jsessionid=2F1668CB406280569390395283F5E7E1;jsessionid=65F40A1B4023F4E8C41287FEEB7809F4 (gene)


Gene Symbol:
Mmp14 Rattus norvegicus Rattus norvegicus
Full name:
matrix metallopeptidase 14
Synonyms:
Mt1-mmp, matrix metalloproteinase-14, MMP-14, MT-MMP 1, MT1MMP, MTMMP1, matrix metallopeptidase 14 (membrane-inserted), matrix metalloproteinase 14 membrane-inserted, membrane type 1-matrix metalloproteinase, membrane-type matrix metalloproteinase 1
Genomic Location:
Chr 15: 32493852-32503077
Description:
enzyme which is an activator of progelatinase A
Orthologs:
Homo sapiens Mus musculus D. melanogaster Macaca mulatta Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_031056
Protein Names
Q6IN06
Q10739



GO Molecular Function

metallopeptidase activity | cation binding | metalloendopeptidase activity | protein-containing complex binding | signaling receptor binding | hydrolase activity | catalytic activity | exopeptidase activity | ion binding | integrin binding | metalloexopeptidase activity | cell adhesion molecule binding | protein binding | zinc ion binding | aminopeptidase activity | metalloaminopeptidase activity | transition metal ion binding | endopeptidase activity | metal ion binding | peptidase activity

GO Biological Process

metallopeptidase activity | positive regulation of striated muscle cell differentiation | positive regulation of locomotion | regulation of B cell activation | cell motility | cranial skeletal system development | developmental process involved in reproduction | regulation of cellular localization | ovarian follicle development | proteolysis | regulation of localization | morphogenesis of an epithelium | gonad development | female gonad development | regulation of immune system process | response to hormone | negative regulation of cellular process | positive regulation of developmental process | protein processing | positive regulation of lymphocyte activation | bone development | regulation of protein localization to membrane | cell differentiation | negative regulation of adherens junction organization | respiratory tube development | negative regulation of cell-matrix adhesion | nervous system development | endochondral bone morphogenesis | neurogenesis | positive regulation of cellular component movement | blood vessel morphogenesis | cellular process | positive regulation of macrophage migration | regulation of cell motility | localization | epithelial tube morphogenesis | zymogen activation | tissue remodeling | metalloendopeptidase activity | negative regulation of signaling | reproductive system development | response to odorant | response to hypoxia | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | endothelial cell proliferation | tissue development | regulation of cell differentiation | positive regulation of muscle cell differentiation | regulation of myotube differentiation | regulation of cellular process | positive regulation of cell growth | regulation of metabolic process | gliogenesis | catabolic process | positive regulation of cellular protein metabolic process | epithelium development | development of primary sexual characteristics | head development | positive regulation of protein processing | response to stimulus | vasculature development | regulation of cellular protein localization | respiratory system development | collagen catabolic process | positive regulation of immune system process | positive regulation of protein metabolic process | negative regulation of cell adhesion | response to stress | craniofacial suture morphogenesis | tube morphogenesis | development of primary female sexual characteristics | positive regulation of cell activation | reproduction | embryonic skeletal system development | cardiovascular system development | positive regulation of proteolysis | regulation of protein processing | regulation of cell adhesion | embryo development | positive regulation of B cell differentiation | regulation of lymphocyte differentiation | blood vessel development | astrocyte cell migration | locomotion | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | regulation of adherens junction organization | multicellular organism development | cell migration | positive regulation of lymphocyte differentiation | regulation of gene expression | positive regulation of cellular metabolic process | exopeptidase activity | regulation of lymphocyte activation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of cell migration | glial cell migration | regulation of cell-substrate adhesion | regulation of Notch signaling pathway | regulation of cellular component movement | endoderm formation | endochondral ossification | response to oxidative stress | positive regulation of cell differentiation | positive regulation of cell migration | cell proliferation | regulation of cellular protein metabolic process | negative regulation of cell-substrate adhesion | angiogenesis | protein maturation | regulation of leukocyte migration | metalloexopeptidase activity | response to estrogen | chordate embryonic development | regulation of cellular metabolic process | skeletal system morphogenesis | regulation of protein metabolic process | bone morphogenesis | regulation of locomotion | embryo development ending in birth or egg hatching | positive regulation of B cell activation | embryonic morphogenesis | embryonic organ morphogenesis | embryonic cranial skeleton morphogenesis | development of primary male sexual characteristics | aminopeptidase activity | protein metabolic process | regulation of growth | response to organic substance | tissue morphogenesis | regulation of hemopoiesis | branching morphogenesis of an epithelial tube | epithelial cell proliferation | male sex differentiation | response to mechanical stimulus | regulation of focal adhesion assembly | anatomical structure development | metalloaminopeptidase activity | embryonic skeletal system morphogenesis | metabolic process | regulation of protein localization to plasma membrane | positive regulation of leukocyte activation | embryonic organ development | male gonad development | organic substance metabolic process | regulation of B cell differentiation | animal organ development | gene expression | regulation of cell activation | positive regulation of leukocyte migration | regulation of striated muscle cell differentiation | lung development | morphogenesis of a branching epithelium | anatomical structure formation involved in morphogenesis | regulation of cell communication | positive regulation of protein maturation | negative regulation of signal transduction | positive regulation of growth | response to organic cyclic compound | endopeptidase activity | endodermal cell differentiation | endoderm development | morphogenesis of a branching structure | anatomical structure morphogenesis | collagen metabolic process | reproductive structure development | regulation of developmental process | developmental process | regulation of muscle cell differentiation | regulation of cell growth | negative regulation of focal adhesion assembly | tube development | regulation of cell junction assembly | formation of primary germ layer | positive regulation of metabolic process | ossification | skeletal system development | gastrulation | negative regulation of Notch signaling pathway | peptidase activity | female sex differentiation | regulation of protein localization | sex differentiation | positive regulation of cell motility | circulatory system development | regulation of cellular component organization | positive regulation of myotube differentiation | regulation of signaling | positive regulation of gene expression | regulation of cell-matrix adhesion | chondrocyte proliferation | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | extracellular matrix | macropinosome | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | intermediate filament cytoskeleton | melanosome | endomembrane system | plasma membrane | vesicle | endosome | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | cell periphery | cytosol | intracellular vesicle | cytoskeleton | intracellular | membrane